Longevity
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in your body, playing a central role in converting food into cellular energy and supporting DNA repair. Research has consistently shown that NAD+ levels decline measurably with age — by some estimates, dropping by roughly half between early adulthood and your 60s.
This decline has been linked in laboratory and early clinical research to reduced cellular energy production, slower DNA repair, and changes in how efficiently mitochondria function. That's led to significant interest in whether restoring NAD+ levels through supplementation or IV/injectable therapy might support healthier aging.
It's worth being clear-eyed about where the evidence currently stands: most of the dramatic findings on NAD+ restoration come from animal studies. Human research is growing but still developing, and results on subjective outcomes like energy and mental clarity are more consistently reported than measurable changes in aging biomarkers.
That said, many patients pursuing NAD+ therapy report meaningful improvements in energy and focus, and the safety profile for supervised NAD+ treatment is well established. As with any longevity intervention, it's one tool among several — not a replacement for foundational habits like sleep, exercise, and nutrition.